This quote is suggesting that if one professes to believe in the Bible, they should engage with it in a meaningful, comprehensive way, rather than selectively choosing which parts to accept and which to ignore. To “do business” with it implies a deep, interactive relationship with the text, where one grapples with its complexities, contradictions, and challenges, instead of merely “screening it out” or dismissing the parts that are uncomfortable or difficult to understand.

In the context of personal development, the idea could be applied to any belief system or set of values one holds. It’s about fully committing to your beliefs, being willing to question and examine them, and not shying away from the difficult parts. This could mean, for example, not just accepting the parts of your belief system that are easy or convenient, but also confronting the parts that challenge you or make you uncomfortable.

In today’s world, this quote could be seen as a call for religious individuals, particularly Christians, to engage more deeply with their faith. With the rise of ‘cafeteria Christianity’ where individuals pick and choose what suits their lifestyle and ignore the rest, this quote serves as a reminder that faith should be more than just a convenience. It should be a challenging, transformative force that shapes one’s entire worldview and lifestyle.

Moreover, the idea could also be applied beyond religious contexts, to any system of thought or belief. It encourages intellectual honesty and consistency, urging individuals to fully engage with their beliefs, question them, and be willing to change their minds if necessary. It’s a call for critical thinking and open-mindedness, qualities that are crucial in today’s complex, diverse, and rapidly changing world.