This quote suggests that much of the world’s problems stem from human restlessness and the inability to be content in solitude. It implies that we often create issues because of our inability to sit still, both literally and metaphorically. The "room" could be seen as a metaphor for one’s own company or mind. Thus, the inability to sit still in a room might mean an inability to be at peace with oneself, to be alone with one’s thoughts, or to be content in one’s own company.

From a broader perspective, this quote could be interpreted as a commentary on human nature. It suggests that humans are inherently restless, always seeking change, action, or progress, even when it might lead to trouble or conflict. This restlessness could manifest in various ways, such as greed, ambition, curiosity, or the desire for power, all of which can lead to trouble.

In today’s world, this idea is highly relevant. We live in an age of constant stimulation and distraction, where solitude and stillness are often undervalued. This constant seeking for stimulation, whether through social media, news, or entertainment, can lead to anxiety, stress, and other problems. It can also prevent us from reflecting on our actions and their consequences, leading to thoughtless or harmful behavior.

In terms of personal development, this quote could serve as a reminder of the importance of mindfulness and self-reflection. It suggests that by learning to be comfortable in our own company, to sit still and reflect on our thoughts and actions, we can avoid many problems. This could mean practicing meditation, spending time in nature, or simply setting aside quiet time each day for reflection. By doing so, we can develop a better understanding of ourselves, our motivations, and our actions, which can lead to personal growth and better decision-making.