This quote suggests that presumption, or making assumptions without sufficient evidence, can first blind a person to reality, then set them on a misguided path. The blindness refers to an inability to see the truth as a result of preconceived notions. The running signifies acting on those false assumptions, leading to potential mistakes or failure.

Presumption can often be born out of arrogance or ignorance. When we presume, we close our minds to other possibilities, effectively blinding ourselves. Once blinded, we act based on our presumptions, taking us down a path that may not be aligned with reality or truth. This path, built on false assumptions, can lead to unexpected and often undesirable outcomes.

In today’s world, this concept is highly relevant. For instance, in the realm of social media, people often presume based on snippets of information they see online, leading to misunderstandings and conflicts. Similarly, in politics, presumptions and biases can lead to polarization, where diverse viewpoints are not considered or respected.

In terms of personal development, it’s essential to avoid presumption. Instead, one should maintain an open mind, always willing to learn and adapt. By doing so, we can see things more clearly and act based on reality rather than assumptions. This approach enables personal growth and helps avoid potential pitfalls that come from acting on presumptions. It promotes critical thinking, empathy, and understanding, all of which are key to personal and professional success.