This quote suggests that minor misunderstandings or disagreements, if left unaddressed, can lead to significant conflict and discord. The “trifles” refer to seemingly insignificant issues or problems, while “great issues” represent larger, more consequential conflicts or dilemmas. The idea is that even the smallest of issues can escalate and have a profound impact on the overall state of affairs, be it in a society or an individual’s life.

In the context of today’s world, this could be seen in the realm of politics where minor policy disagreements can escalate into major partisan divides, leading to a state of civil unrest and confusion. Similarly, on a personal level, a small misunderstanding or disagreement in a relationship, if not addressed promptly and effectively, can fester and grow, leading to significant strife and possibly even the end of the relationship.

In terms of personal development, this quote is a reminder of the importance of addressing issues, no matter how small, as soon as they arise. It encourages us to not dismiss minor problems or conflicts as inconsequential, but to deal with them immediately and effectively to prevent them from escalating into larger, more difficult to manage situations. It also suggests that the resolution of small issues can have a significant impact on our overall growth and development as individuals.

Therefore, the quote serves as a reminder to pay attention to the small things in life, as they often have the greatest impact. It encourages us to be mindful, proactive, and decisive, whether in the management of societal affairs or our personal lives.