This quote explores the concept of human ignorance towards our past and future. When Pope refers to ‘former’ and ‘future’ fate, he means our past and future lives or states of existence. He suggests that humans are blind to both, unable to know our past lives or predict our future ones.

The ‘pre-existent state’ signifies our past lives or existence before our current life. Pope is essentially asking who among us can truly know or remember what we were before we came into our present existence. This question taps into philosophical and spiritual debates about reincarnation, past lives, and the continuity of the soul.

Applying this idea to today’s world or personal development, it suggests that we should focus on the present moment because we cannot change our past or predict our future. It underlines the importance of mindfulness and being ‘in the moment’, as that’s the only state we can truly know and influence.

On a broader societal level, it could be interpreted as a call for humility. No matter how much we achieve or how far we advance, there will always be things beyond our comprehension. This quote reminds us to recognize our limitations and not be arrogant about our knowledge or capabilities.

In terms of personal development, it encourages self-awareness and acceptance. By acknowledging that we don’t know everything about ourselves (our past or future), we can be more open to growth and change. It also helps us to let go of past mistakes or future anxieties, focusing instead on what we can do now to improve and evolve.